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The mission of the APRV Network is to disseminate information regarding the unique mechanical breath profile (MBP) of the Time Controlled Adaptive Ventilation (TCAV) method of the mode Airway Pressure Release Ventilation (APRV).  This method was designed by Nader M. Habashi, MD and has been widely studied in various animal models and clinically.  This website is meant to be a landing page for those interested in the science behind the TCAV method and for those looking for a deeper understanding. Science is the only way to truth.  This website will present scientifically driven work in both the basic science and clinical environment.


The APRV Network is built on the idea of providing the science behind the methodology of a unique method of applying the mode Airway Pressure Release Ventilation (APRV) to produce a mechanical breath profile (MBP) that provides alveolar stability.  This Time Controlled Adaptive Ventilation (TCAV) Method has been utilized by Nader M. Habashi, MD, FACP, FCCP of the R Adams Shock Trauma Center in Baltimore, Maryland.  Over 20 years of bedside experience with the TCAV method led Dr. Habashi to a better understanding of the interaction between the patient and the mechanical ventilator and personalizing the mechanical breath.  It became apparent that a “one-size-fits-all” approach to mechanical ventilation was not appropriate to a patient population where disease pathology varies.  By understanding the viscoelastic nature of the respiratory system, a clinician can personalize the MBP for patients based on the feedback loop of the expiratory slope.  This TCAV method may finally be the answer clinicians and researchers have been looking for to personalize mechanical ventilation for each patient.